Non-Alcoholic Fatty Liver Disease (NAFLD)

  • 03 Apr 2025

In News:

  • Ranchi, Jharkhand, is poised to become the first district in the state to launch a comprehensive campaign for the screening and management of Non-Alcoholic Fatty Liver Disease (NAFLD), now redefined as Metabolic dysfunction-associated steatotic liver disease (MASLD).
  • The initiative will be carried out under the National Programme for Prevention and Control of Non-Communicable Diseases (NP-NCD).
  • The campaign will begin on April 19, marking World Liver Day, and aims to raise awareness and strengthen early detection and treatment of liver disorders in the population.

About NAFLD/MASLD:

  • NAFLD refers to fat accumulation in the liver not caused by alcohol consumption.
  • It includes two types:
    • Non-Alcoholic Fatty Liver (NAFL) – mild form.
    • Non-Alcoholic Steatohepatitis (NASH) – severe form, can progress to cirrhosis, liver failure, or cancer.
  • It is increasingly prevalent in individuals with obesity, type 2 diabetes, hypertension, and metabolic syndrome.
  • NAFLD is asymptomatic in early stages but can elevate the risk of cardiovascular disease, kidney disease, and diabetes-related complications.
  • Affects all age groups, including children.

Key Features of the Ranchi NAFLD Initiative:

  • Two-phase Screening Drive:
    • Phase 1 (April–June): Focus on 30,000 high-risk individuals—those with obesity, diabetes, or hypertension.
    • Phase 2 (July–November): Screening expanded to all adults over 18 years in the district.
  • Technical Support: Provided by the Institute of Liver and Biliary Sciences (ILBS), New Delhi.
  • Mobile Screening Vans:
    • Each van costs approx. ?1 crore.
    • Equipped with FibroScan, an advanced, non-invasive liver diagnostic tool.
    • Services provided free of cost in both urban and rural areas.
  • Capacity Building:
    • 30–40 district-level officers to be trained as master trainers.
    • Frontline healthcare workers will be trained to conduct screenings and data collection.
  • Health System Strengthening:
    • Referral mechanisms to ensure patients receive specialised care.
    • Data tracking system to maintain records until integration with the national NCD portal.

Public Health Significance:

  • As per the district's civil surgeon, 50% of OPD cases are liver-related.
  • On average, 25 patients/day are diagnosed with liver disease; five require hospitalisation.
  • Early detection through such initiatives can help prevent disease progression and mortality.

Treatment & Prevention of NAFLD:

  • No specific drug currently exists for NAFLD.
  • Weight loss remains the primary treatment—shown to reduce liver fat, inflammation, and fibrosis.
  • Management of comorbidities like high blood pressure, high cholesterol, and diabetes is also recommended.